@article{SeifJMRI2016,
	abstract = {PURPOSE: To investigate if image registration of diffusion tensor imaging (DTI) allows omitting respiratory triggering for both transplanted and native kidneys MATERIALS AND METHODS: Nine kidney transplant recipients and eight healthy volunteers underwent renal DTI on a 3T scanner with and without respiratory triggering. DTI images were registered using a multimodal nonrigid registration algorithm. Apparent diffusion coefficient (ADC), the contribution of perfusion (FP ), and the fractional anisotropy (FA) were determined. Relative root mean square errors (RMSE) of the fitting and the standard deviations of the derived parameters within the regions of interest (SDROI ) were evaluated as quality criteria. RESULTS: Registration significantly reduced RMSE in all DTI-derived parameters of triggered and nontriggered measurements in cortex and medulla of both transplanted and native kidneys (P < 0.05 for all). In addition, SDROI values were lower with registration for all 16 parameters in transplanted kidneys (14 of 16 SDROI values were significantly reduced, P < 0.04) and for 15 of 16 parameters in native kidneys (9 of 16 SDROI values were significantly reduced, P < 0.05). Comparing triggered versus nontriggered DTI in transplanted kidneys revealed no significant difference for RMSE (P > 0.14) and for SDROI (P > 0.13) of all parameters. In contrast, in native kidneys relative RMSE from triggered scans were significantly lower than those from nontriggered scans (P < 0.02), while SDROI was slightly higher in triggered compared to nontriggered measurements in 15 out of 16 comparisons (significantly for two, P < 0.05). CONCLUSION: Registration improves the quality of DTI in native and transplanted kidneys. Diffusion parameters in renal allografts can be measured without respiratory triggering. In native kidneys, respiratory triggering appears advantageous. J. Magn. Reson. Imaging 2016.},
	address = {Department of Clinical Research and Radiology, University of Bern, Bern, Switzerland.},
	address1 = {Department of Nephrology, Hypertension and Clinical Pharmacology, University Hospital of Bern, Switzerland.},
	address2 = {Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland.},
	address3 = {Department of Clinical Research and Radiology, University of Bern, Bern, Switzerland.},
	address4 = {Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland.},
	address5 = {Department of Nephrology, Hypertension and Clinical Pharmacology, University Hospital of Bern, Switzerland.},
	address6 = {Department of Clinical Research and Radiology, University of Bern, Bern, Switzerland.},
	author = {Seif M. and Mani L. and Lu H. and Boesch C. and Reyes M. and Vogt B. and Vermathen P.},
	copyright = {(c) 2016 The Authors, Journal of Magnetic Resonance Imaging published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.},
	crdt = {2016/02/13 06:00},
	da = {20160212},
	date = {2016 Feb 12},
	date-added = {2016-03-30 12:55:17 +0000},
	date-modified = {2017-01-09 17:44:32 +0000},
	dep = {20160212},
	doi = {10.1002/jmri.25176},
	edat = {2016/02/13 06:00},
	issn = {1522-2586 (Electronic); 1053-1807 (Linking)},
	jid = {9105850},
	journal = {J Magn Reson Imaging},
	jt = {Journal of magnetic resonance imaging : JMRI},
	keywords = {DTI; diffusion; kidney; motion correction; nonrigid image registration; respiratory triggering},
	language = {ENG},
	lid = {10.1002/jmri.25176 {$[$}doi{$]$}},
	lr = {20160213},
	mhda = {2016/02/13 06:00},
	month = {Feb},
	number = {2},
	oto = {NOTNLM},
	own = {NLM},
	pages = {327--334},
	phst = {2015/11/03 {$[$}received{$]$}; 2016/01/19 {$[$}accepted{$]$}},
	pmid = {26871263},
	pst = {aheadofprint},
	pt = {JOURNAL ARTICLE},
	status = {Publisher},
	title = {Diffusion tensor imaging of the human kidney: Does image registration permit scanning without respiratory triggering?},
	volume = {44},
	year = {2016},
	Bdsk-File-1 = {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},
	Bdsk-Url-1 = {http://dx.doi.org/10.1002/jmri.25176}}